- Aprasulfcity
For vet. use only
( W. S. P. ) .
Composition:
Each 84 gm contains:
Apramycin sulphate 72.6 gm (Eq. to Apramycin base 50 gm)
Properties:
Apramycin is an aminoglycoside that is a bactericidal against many gram-negative bacteria (E. coli, Pseudomonas, Salmonella, klebsiella, Proteus, Pasturella, Treponema hyodysenteriae, Bordetella bronchiseptica), Staphylococcus and Mycoplasma. Aprasulf- city prevents protein synthesis by susceptible bacteria, presumably by binding to 30S ribosomal subunit.
Indication:
In Poultry: For treatment of colisepticaemia ( colibacillosis ) caused by susceptible strains of E. coli .
In Calves: For treatment of bacterial enteritis in calves caused by E. coli and Salmonella organisms .
Target Species: Poultry , Calves.
Dosage and Administration:
For Active ingredient:
Poultry: by addition to drinking water, 250- 500 mg Apramcin activity / 1 liters for 5 days ( This is equivalent to an average of 40-80mg apramycin activity per kg body weight ).
Calves: by addition to drinking water, milk, or milk replacer, 20 – 40 mg Apramycin activity / kg body weight daily.
For whole Product:
Poultry: by addition to drinking water, 0.5 – 1 gm / 1 liter for 5 days.
Calves: by addition to drinking water, milk, or milk replacer, 4 -7 gm / 10 liters & continue treatment for 5 days.
Warning & precautions:
- Aminoglycoside may cause hypersensitivity reactions in operators following injection, inhalation, ingestion, or skin contact.
- Caution in renal impairment.
- Should not be used in birds producing eggs for human consumption.
Contraindication:
- Hypersensitivity to Apramycin.
- Aprasulfcity should not be used in cats and in animals with myasthenia gravis.
Side effects:
- Ototoxicity and nephrotoxicity are a distinct possibility.
Withdrawal time:
Poultry: Slaughter 7 days Calves: Slaughter 28 days.
Storage condition:
- In dry and cool place at temperature not exceeding 30˚C.
Packing:
- Polyethylene bag inside a tin pack 250 gm and 500 gm.